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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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C. Other Anti-hypertensive Drugs

Cialis, containing the active ingredient tadalafil, is commonly prescribed for the treatment of blood pressure levels 2.5 and 6.5 mmHg in people 18 and older. It is a phosphodiesterase type 5 (PDE5) inhibitor and works by increasing blood flow to the penis.

D. Other Drug-Food Interactions

Cialis, containing the active ingredient tadalafil, can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions:

  1. : Though not a direct interaction, combining Cialis with high alcohol consumption might worsen side effects like headaches or increase tadalafil effectiveness in sensitive individuals.
  2. : While while improving erectile function while using Cialis, avoiding consuming it with a high-fat meal may delay its onset of action.

Erectile Dysfunction

Erection problems (impotence) are very common, particularly in men over 40.

Most men occasionally fail to get or keep an erection. This is usually due to stress, tiredness, anxiety or drinking too much alcohol, and it’s nothing to worry about.

If it happens more often, it may be caused by physical or emotional problems.

Physical causes Possible cause Treatment Narrowing of penis blood vessels, high blood pressure, high cholesterol medicine to lower blood pressure, statins to lower cholesterol Hormone problems hormone replacement – for example, testosterone Side effects of prescribed medication change to medicine following discussion with GP You may also be asked to make lifestyle changes.

Do lose weight if you’re overweight stop smoking eat a healthy diet exercise daily try to reduce stress and anxiety

Don’t cycle for a while (if you cycle more than 3 hours a week) drink more than 14 units of alcohol a week

  • Side Effects

    Possible side effects

    Like all medicines, this medicine can cause side effects, although not everybody gets them. These effects are normally mild to moderate in nature.

    If you experience any of the following side effects stop using the medicine and seek medical help immediately:

    allergic reactions including rashes (frequency uncommon). chest pain – do not use nitrates but seek immediate medical assistance (frequency uncommon). priapism, a prolonged and possibly painful erection after taking CIALIS (frequency rare). If you have such an erection, which lasts continuously for more than 4 hours you should contact a doctor immediately. sudden loss of vision (frequency rare). Other side effects have been reported:

    Common (seen in 1 to 10 in every 100 patients)

    headache, back pain, muscle aches, pain in arms and legs, facial flushing, nasal congestion, and indigestion. Uncommon (seen in 1 to 10 in every 1,000 patients)

    dizziness, stomach ache, feeling sick, being sick (vomiting), reflux, blurred vision, eye pain, difficulty in breathing, presence of blood in urine, prolonged erection, pounding heartbeat sensation, a fast heart rate, high blood pressure, low blood pressure, nose bleeds, ringing in the ears, swelling of the hands, feet or ankles and feeling tired. Rare (seen in 1 to 10 in every 10,000 patients)

    fainting, seizures and passing memory loss, swelling of the eyelids, red eyes, sudden decrease or loss of hearing, hives (itchy red welts on the surface of the skin), penile bleeding, presence of blood in semen and increased sweating. Heart attack and stroke have also been reported rarely in men taking CIALIS. Most of these men had known heart problems before taking this medicine.

    Partial, temporary, or permanent decrease or loss of vision in one or both eyes has been rarely reported.

  • estrogens and male infertility control

    Like all medicines, this medicine can cause side effects, but not everybody gets them. This is because CIALIS does not act on estrogen receptors.

    There is a risk of side effects when there is a lack of estrogen, reductase inhibitors or the estrogen- PINISO can cause a serious drop in blood pressure, making the heart more likely to pump blood more easily.

    Mostly pregnant women avoided duringlast year

    Discussing whether you should be taking this medicine with your pharmacist is recommended. This may affect your ability to get an erection. They may change the dose of this medicine you are taking. This medicine is in pregnancy, not sesameights11. This medicine is only used if you are pregnant. This medicine is shipped off to your pharmacist in amygdalacision11.

    If you have been told by your pharmacist that you are pregnant you should not take CIALIS.

    common side effects of CIALIS

    Like all medicines, this medicine can cause side effects, mostly mild to moderate in nature. Common side effects

    The most common side effects of CIALIS are:

    headache, back pain, muscle aches, reflux, dizziness, stomach ache, tiredness, reflux, indigestion, reduced libido, sexual dysfunction and low libido.

    A recent study has shown that the medication Cialis is effective in preventing the development of benign prostatic hyperplasia (BPH), or enlarged prostate. This study compared the efficacy of Cialis with the standard dose of Viagra, the active ingredient in both the two medications, in over 100 men with BPH, who had undergone radical prostatectomy, or prostatectomy that had been unsuccessful in reducing the risk of progression to urinary symptoms (symptoms of prostate cancer and urinary incontinence).

    The study included a total of 56 men with a median age of 62.5 (IQR of 62.9-65.9) with BPH, who were randomly assigned to Cialis or Viagra for the first time at a random time. The mean dosage of the two medications was 12.9 mg Cialis and 17.3 mg Viagra. The median follow-up time was 4.9 months for Cialis and 4.2 months for Viagra, with a higher rate of improvement in BPH patients compared to the standard dose.

    Of the 56 men, the mean change from baseline in urinary incontinence (defined as the inability to perform urine flow) was significantly higher in the Cialis group (11.2) compared to the Viagra group (8.5) (p=0.002). This study demonstrates that Cialis and Viagra are equally effective in preventing the development of BPH. This finding emphasizes the need to further explore the effectiveness of these two medications in the treatment of BPH and the importance of the individual patient and the treatment duration.

    This study will further help identify the optimal dosage of the two medications that offer the greatest benefits in the treatment of BPH.

    Key Findings

    Based on the findings, the study of the effectiveness of Cialis and Viagra is expected to provide valuable information for healthcare professionals to better understand the clinical benefits and risks of these two medications. Cialis, a widely prescribed medication for the treatment of erectile dysfunction, has been shown to be effective in the treatment of BPH.

    The results of the study show that Cialis has been shown to be more effective than Viagra in preventing the development of BPH. This is important as the presence of prostate cancer is a common condition that can lead to BPH, which is more common in men over 40.

    However, Viagra has been shown to be effective in preventing the development of BPH. This is an important finding because BPH can lead to more serious complications, such as urinary incontinence and possibly death. The findings of this study demonstrate that the medication Cialis is effective in preventing the development of BPH, which may be a sign that the medication is working for the best. It is important for patients and healthcare providers to consider these factors when deciding whether or not to continue with the medication.

    Cialis, the brand name for the medication, has been available for many years. Cialis is a prescription medication that contains the active ingredient tadalafil, a drug that is used to treat erectile dysfunction. It is one of the most widely used and effective medications for treating erectile dysfunction, providing men with an effective and long-lasting solution for erectile dysfunction.

    The medication has been shown to be more effective than Viagra in preventing the development of BPH. The results of the study show that Cialis is more effective than Viagra in preventing the development of BPH.

    Overall, the study shows that the medication Cialis is effective in preventing the development of BPH, which may be a sign that the medication is working for the best.

    About Dr. Baker

    Dr. Baker is a board-certified urologist specializing in male reproductive medicine. She has over 30 years of experience in male reproductive medicine, including male reproductive endocrinology, gynecology, and reproductive medicine. Baker is passionate about providing quality care to men and women with medical conditions that impact their sexual health. She is dedicated to improving the quality of life for men and women, ultimately leading to better health outcomes for those who live with BPH.

    Contact us at 800-552-3577 to learn more or to apply for a position as a Qualified Nurse Specialist.

    Cialis, sold under the brand name Cialis, is an FDA-approved medication used primarily to treat erectile dysfunction (ED) in men. It is also used to treat benign prostatic hyperplasia (BPH), which is a condition in which the prostate gland enlarges and causes an inability to pass urine. Cialis belongs to a class of drugs called phosphodiesterase type 5 (PDE 5) inhibitors.

    Cialis works by relaxing the smooth muscles in the prostate and bladder, allowing urine to flow more easily. This allows the urinary tract to expand and relieve symptoms, such as urinary frequency and urgency.

    However, Cialis is not for everyone. Individuals with an erection that lasts for more than four hours or with a severe heart condition should not take the drug.

    Who should not take Cialis?

    Cialis is not for everyone. Men who take nitrates for chest pain or have had a heart attack or stroke must not take the medication.

    Men with a history of blood clots, stroke, or liver or kidney disease who take blood pressure medications, such as nitrates, should not take Cialis.

    Women who take birth control pills should not take Cialis.

    What should I tell my healthcare provider before taking Cialis?

    Before taking Cialis, tell your healthcare provider if you have ever had an allergic reaction to tadalafil, any other medications, or any of the ingredients in Cialis tablets. If you have a history of heart problems, strokes, high or low blood pressure, high cholesterol or diabetes, or any other medical conditions, tell your healthcare provider.

    Cialis may increase the risk of vision loss or other eye problems, such as cataracts, retinitis pigmentosa, changes in color vision, or changes in the amount of urine passed. If you experience sudden decrease or loss of vision in one or both eyes, stop taking Cialis and call your healthcare provider immediately.